Description
ENCLOMIPHENCITRAT DRIADA MEDICAL ENCLOMILAD 12.5 MG 50 TAB
Enclomiphencitrat Driada Medical Enclomilad 12.5 mg is a derivative of clomiphene citrate. Enclomiphene is a relatively new drug, not only more effective than clomiphene (Clomiphene) is, but also avoids many of the side effects of its predecessor.
Clomiphene consists of the two isomers zuclomiphene (Zuclomiphene) and enclomiphae (Enclomiphen). Zuclomiphene is an estrogen agonist and is associated with a number of side effects, for example, a reduced libido, while enclomifene has an antiestrogenic effect in the same tissues.
Information about Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg
Enclomiphencitrat Driada Medical Enclomilad 12.5 mg is an antagonist of estrogen receptors. It blocks estrogen and leads to it, that the body releases the LH- and FSH levels increased. This stimulates the testicles to do so, to produce more testosterone and sperm. And unlike testosterone replacement therapy (TRT), in which your body's natural testosterone production is replaced with a synthetic version, Enclomiphene helps your body, to produce more natural testosterone. This will help you, the side effects associated with synthetic testosterone such as testicular contraction, To avoid prostate enlargement and cardiovascular problems.
Enclomiphene can be used to increase testosterone levels, independently of, whether you have low testosterone levels or just want an advantage in terms of your energy, Your confidence, want to improve your sexual function and your athletic performance.
Mechanism of action
Enclomiphene has a selective estrogen receptor modulator effect (SERM), what means, that it interacts with estrogen receptors in the body, However, it has different effects in different tissues. As a result, it can occur in some tissues, such as the mammary glands, have a blocking effect on estrogens, in others, for example in bone tissue, however not. This allows the use of enclomifene to treat various medical conditions, which are associated with an imbalance of estrogens in the body.
Encomiphen is a selective antagonist of estrogen receptors, which counteracts estrogen receptors in the pituitary gland and disrupts the negative feedback loop of estrogen in relation to the hypothalamic-pituitary-gonadal axis, which ultimately leads to an increase in the secretion of gonadotropins – LH and FSH – and a subsequent increase in the level of testosterone circulating in the blood.
Enclomiphen vs. Clomiphene
Clomiphene Clomilad consists of two isomers: Enclomiphene and zuclomiphene.
While enclomifene blocks the binding of estrogen to estrogen receptors in the hypothalamus and pituitary gland of the brain, Zuclomifene increases estrogen levels and accumulates over time.
Enclomiphen Citrate Driada Medical Enclomilad 12.5 mg is superior to clomiphene, as it has fewer side effects and remains in the body for a shorter time.
Clomiphene is a selective estrogen receptor modulator (SERM), a class of drugs, which affects estrogen production. By blocking the production of estrogen, Clomid “tricks” the body, by making him believe, that he is not getting enough estrogen, and thereby stimulates the production of the hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It helps with women, to stimulate ovulation. In men, an increase in LH contributes- and FSH levels to stimulate testosterone production and spermatogenesis.
Facts about Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg
Despite its popularity in treating low testosterone levels, some studies show, that the use of clomiphene can have disadvantages, mainly due to the zuclomiphene it contains. Zuclomiphene has side effects, that go beyond the therapeutic effect of the drug. For these reasons, the researchers came to this conclusion, that due to the completely different biochemical and toxicological properties of the two isomers “there is a need, “to develop a pure selective estrogen receptor antagonist” for the treatment of men with low testosterone levels.
When comparing Clomid to enclomiphene, researchers found, that enclomiphene wins. With fewer side effects and greater benefits, Encomiphen is the preferred choice for safely increasing testosterone levels. It was shown, that zuclomiphene has a “harmful” effect on the male reproductive tract. In addition to significantly reducing the size of the testicles during testicular degeneration, zuclomifene also caused the loss of Leydig cells, the absence of spermatozoa in the seminiferous tubules and a reduction in the size of the epididymis, seminal vesicles and kidneys.
Due to its mixed estrogenic and anti-estrogenic effects, clomiphene can also cause emotional regulation disorders such as mood swings and depression. It is believed, that this is due to an estrogen imbalance, that is caused by this, that zuclomifene remains in the body longer than enclomifene.
Other reported side effects of clomiphene include irritability, Anxiety and decreased libido.
Hypogonadism in men
Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg was developed as an alternative to testosterone for the treatment of hypogonadism in men, to maintain sperm production and reduce the risk of negative side effects associated with taking testosterone. This contributes to this, to restore normal testosterone levels in the body and improve sperm quality.Hypogonadism in men
Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg was developed as an alternative to testosterone for the treatment of hypogonadism in men, with the goal, maintain sperm production and reduce the risk of negative side effects associated with testosterone use. It helps, restore normal testosterone levels in the body and improve sperm quality.
Female infertility
Clomiphene can be used in combination with other medications to stimulate ovulation in women, who have difficulties, to get pregnant.
Estrogen-dependent diseases
Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg can be used to treat breast tumors, who are estrogen dependent. It helps, reduce estrogen levels in the body, which can slow the growth of the tumor.
Treatment of hypogonadism
Hypogonadism is a pathological process, caused by a lack of male sex hormones, especially testosterone, is caused and has numerous consequences for the male body.
As you know, Many body functions suffer when testosterone is reduced, such as fertility, and fatigue occurs, muscle mass decreases, the fat content increases, depression develops and erectile dysfunction occurs. Most often, testosterone levels in a man's body begin to decline 30 years to decline, However, the situation can be caused by obesity, Diabetes and vascular diseases are worsened.
One of the treatment options for hypogonadism is the use of drugs of the SERM class.
In clinical trials, enclomifene was tested in men with secondary hypogonadism. As a result of the research it turned out, that enclomiphene citrate increases testosterone levels, the levels of follicle-stimulating hormone and luteinizing hormone, that are important for reproductive health, increased, while sperm count did not decrease.
In men with secondary hypogonadotropic hypogonadism, an increase in LH and FSH improves testosterone levels and sperm motility. Men with secondary hypogonadotropic hypogonadism have abnormally low testosterone levels due to low normal levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). The biological role of these hormones is this, to stimulate the endogenous testosterone production of the testes.
Enclomiphene treatment works differently than traditional testosterone replacement therapy, in which testosterone is replaced by an exogenous source, and has a number of benefits – such as improving rather than reducing fertility, a stimulation of the production of endogenous testosterone instead of the introduction of exogenous testosterone, which ultimately does not lead to suppression of the production of its own testosterone, as well as the absence of negative effects on cholesterol levels and increased hematocrit levels.
Why do bodybuilders use Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg?
In addition, testosterone levels remain in patients, die Enclomiphene Citrate Driada Medical Enclomilad 12.5 take mg, increased even after discontinuation of treatment.
The effectiveness and safety of Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg in the treatment of male hypogonadism has been studied in several clinical trials. Such a study, die 2014 was published in the Journal of Clinical Endocrinology and Metabolism, showed, that encomiphencitrate improves testosterone levels and sperm parameters in men with hypogonadism.
Another in the Journal of Sexual Medicine in the year 2016 published study also showed, that encomiphencitrate improves testosterone levels and sperm production in men with hypogonadism without significant side effects.
Obwohl Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg is not a first-line drug for the treatment of male hypogonadism, It can be an effective alternative treatment option for men, who cannot or do not want to use testosterone.
Therapy to increase testosterone levels
Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg acts as an antiestrogen, what means, that it blocks the effects of estrogens in the body. In addition to treating low testosterone, this can lead to an increase in testosterone levels, but also to an increase in testosterone levels beyond normal limits, which may bring some benefits in terms of accelerated recovery after training and an increase in psychodynamic-emotional background.
An increase in testosterone levels can also lead to increased athletic performance, more energy, some muscle mass and even more self-confidence.
If you use enclomiphene for these purposes, you need to monitor the levels of hormones such as estradiol and SHBG while taking it. High testosterone levels lead to an increase in these hormones, which can both cause unwanted side effects and negate any benefits of increased testosterone levels.
Studies on Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg
After 10 days of using Enclomiphene Citrate, run Driada Medical Enclomilad 12.5 mg do a blood test for estradiol. When increasing, use aromatase inhibitors such as anastrazol. You should choose the dosage and reduce the estradiol level to the middle of the norm. This should definitely be done, as increased estradiol levels can lead to problems with your psycho-emotional state and also lower libido. If you notice these phenomena when taking enclomifene, it's time, Lower your estradiol levels. We recommend lowering it to the middle of the reference values, but maybe you feel better with the other values. These parameters are determined individually, since estrogens can suppress its production. It can improve muscle growth and increase strength.
You should also use Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg monitor SHBG levels. When this protein exceeds the highest normal limit, you should reduce it with the help of an agent such as mesterolone. The fact is, that a high proportion of this protein binds and prevents your testosterone, that it circulates freely in the blood and binds to androgen receptors, which also reduces the effectiveness of the use of enclomifene, if that is your goal, to increase testosterone levels above normal limits. The dosage of Proviron can be 25-50 mg per day depending on the SHBG level in the blood, every other day or several times a week. Higher dosages can negatively affect the body's testosterone levels.
The study showed, that a single dose of 12.5 mg enclomiphene the testosterone level of 217.2 ng/dl 471.9 ng/dl increased and made it possible, to maintain the increased testosterone concentration over a longer period of time.
The effectiveness and safety of enclomiphene citrate in the treatment of male hypogonadism has been evaluated in several clinical trials. Such a study, die 2014 im Journal of Clinical Endocrinology & Metabolism was published, showed, that enclomiphene citrate improved testosterone levels and semen parameters in men with hypogonadism.
Enclomiphene citrate from Driada Medical for use in bodybuilding
Some studies show, dass Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg may be effective in improving athletic performance. For example, a study published in the International Journal of Sports Medicine showed, that the use of enclomifene in men improved weightlifting results. Of course, taking enclomiphene will in no way replace a full cycle of anabolic steroids, but this can be an intermediate step, if an inexperienced athlete is still afraid of using AS, but already needs accelerated recovery or wants to accelerate progress slightly beyond the values of a “natural athlete”.
The use of enclomiphene for PCT
Enclomiphene Citrate Driada Medical Enclomilad 12.5 mg can be used as a medication for post-course therapy (PCT) be used after taking anabolic steroids. This is the effect effect, which is most interesting for fans of PEDs. Anabolic steroids such as testosterone can suppress the body's natural testosterone production. At the end of the cycle of taking anabolic steroids, testosterone levels in the body may be very low, resulting in undesirable effects such as loss of muscle mass, can lead to a decline in the psycho-emotional background and a deterioration in sexual function .
The follow-up treatment aims to achieve this, restore natural testosterone production in the body. Enclomiphene may be an effective medication for PCT, as it helps restore natural testosterone production by stimulating the hypothalamic-pituitary-testicular axis.
Benefits of Steroids
- Increases testosterone levels in both hypogonadal men and healthy men with the ability to do so
- Increase in testosterone levels above normal limits without negative estrogenic effects, which can be caused by taking its predecessor – clomiphene citrate
Enclomilad 12.5 mg correct dosages
The typical recommended enclomifene dosage is 6.25-25 mg per day
Positive effects
Increasing endogenous testosterone levels
Negative side effects
- Headache
- stomach ache
- nausea
- Hot flashes
- Arthralgia
Bad contraindications
- Pregnant woman,
- Breastfeeding women,
- wWomen with unexplained uterine bleeding
- Women with ovarian growths or cysts, that are not related to polycystic ovary syndrome
- Patients with a history of liver disease
- Patients with uncontrolled adrenal glands- or thyroid dysfunction
- Patient with known allergy to enclomiphene or clomiphene